AChE-IN-81

Product Description: AChE-IN-81 (compound 22) is a potent, irreversible and selective AChE inhibitor. AChE-IN-81 inhibits activity on AChE with inhibitory rates of 80.0%, with an IC50 of 3.7 μM. AChE-IN-81 binds to AChE with a binding affinity (Kd) of 5.37 μM. AChE-IN-81 effectively reduces in zebrafish brain cells. AChE-IN-81 exhibits potential neuroprotective activities on H2O2-induced SH-SY5Y cell injury model[1].

Formula: C37H54ClNO5

References: [1]Zhang F, et al. Targeting Histone Deacetylase 11 with a Highly Selective Inhibitor for the Treatment of MASLD. Adv Sci (Weinh). 2025 Feb 20:e2412903.

Molecular Weight: 628.28

Research Area: Neurological Disease

Target: Apoptosis;Cholinesterase (ChE)

• SKU: MEXHY-170925-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170925-0
• Package Unit: Get quote
• Quantity Unit: STK