AH078

Product Description: AH078 (compound 37) is a PROTAC degrader that selectively targets CK1δ and CK1ε, and has low targeting for CK1α. AH078 consists of PROTAC linker (black part) Monomethyl octanoate (HY-W001958), target protein ligand (red part) (HY-170860) CK1δ/CK1ε liagnd-1 and E3 ligase ligand (blue part) E3 ligase Ligand 58 (HY-170861). Among them, E3 ligase ligand + linker can form a conjugate E3 Ligase Ligand-linker Conjugate 163 (HY-170862)[1].

Applications: Cancer-Kinase/protease

Formula: C51H60F2N10O5S

References: [1]Haag A, et al. Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε. J Med Chem. 2025 Jan 9;68(1):506-530.

Molecular Weight: 963.15

Research Area: Others

Target: Casein Kinase

• SKU: MEXHY-170859-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170859-0
• Package Unit: Get quote
• Quantity Unit: STK