AH2-14c

Product Description: AH2-14c is an inhibitor for DNA demethylase ALKBH2. AH2-14c inhibits the cell viability (IC50 is 4.56 µM) and migration of GBM U87. AH2-14c regulates the expression of apoptosis-related genes, and induces apoptosis in GBM U87 cell[1].

Formula: C23H26N4O3

References: [1]Xu K, et al., Discovery and structure-activity relationship study of nicotinamide derivatives as DNA demethylase ALKBH2 inhibitors. Eur J Med Chem. 2025 Jan 15;282:117054.

Molecular Weight: 406.48

Compound Purity: 98.01

Research Area: Cancer

Solubility: DMSO : 12.5 mg/mL (ultrasonic)

Target: Apoptosis;Histone Demethylase

• SKU: MEXHY-168708-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168708-100
• Package Unit: 100 mg
• Quantity Unit: STK