AKR1C3-IN-15, CAS 3059671-44-9

Product Description: AKR1C3-IN-15 (compound 30) is a potent and selective AKR1C3 inhibitor with an IC50 of 5 nM. AKR1C3-IN-15 enhances Sorafenib (HY-10201)-induced ROS generation, promoted apoptosis, and restored sorafenib sensitivity in HCC models both in vitro and in vivo[1].

Formula: C19H16FNO4

References: [1]Xing S, et al. Discovery of Highly Potent AKR1C3 Inhibitors Treating Sorafenib-Resistant Hepatocellular Carcinoma. J Med Chem. 2025 Apr 10;68(7):7367-7389.

CAS Number: 3059671-44-9

Molecular Weight: 341.33

Research Area: Cancer

Target: Aldose Reductase

• SKU: MEXHY-173453-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173453-0
• Package Unit: Get quote
• Quantity Unit: STK