Aminoxyacetic acid, CAS 645-88-5

Product Description: Aminooxyacetic acid (Carboxymethoxylamine) is a malate-aspartate shuttle (MAS) inhibitor. Aminooxyacetic acid also inhibits the GABA degradating enzyme GABA-T.

Applications: Cancer-programmed cell death

Formula: C2H5NO3

References: [1]Wang C, et al. Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis. Cancer Lett. 2016 Aug 1;378(1):1-7./[2]Pagliusi SR, et al. Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments. Naunyn Schmiedebergs Arch Pharmacol. 1983 Apr;322(3):210-5./[3]Korangath P, et al. Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate. Clin Cancer Res. 2015 Jul 15;21(14):3263-73.

CAS Number: 645-88-5

Molecular Weight: 91.07

Compound Purity: 90.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: GABA Receptor

• SKU: MEXHY-107994A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-107994A-1
• Package Unit: 1 mg
• Quantity Unit: STK