AMPK activator 16, CAS 2252336-04-0

Product Description: AMPK activator 16 (compound 6) is a AMP-activated protein kinase (AMPK) inhibitor. AMPK activator 16 shows the most efficient interactions with the key residues of AMPK and demonstrates significant activation of AMPK. AMPK activator 16 increases the expression of phosphorylated AMPK (p-AMPK) and its downstream signaling proteins, such as phosphorylated ACC (Acetyl-CoA Carboxylase) (p-ACC) and phosphorylated raptor (p-raptor), in N2a cells[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C23H20ClNO5S

References: [1]Jeon KH, et al. Computer-aided discovery of novel AMPK activators through virtual screening and SAR-driven synthesis. Eur J Med Chem. 2025 Apr 5;287:117318.

CAS Number: 2252336-04-0

Molecular Weight: 457.93

Research Area: Metabolic Disease; Neurological Disease

Target: Acetyl-CoA Carboxylase;AMPK

• SKU: MEXHY-170931-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170931-0
• Package Unit: Get quote
• Quantity Unit: STK