AMPK-IN-6

Product Description: AMPK-IN-6 (compound 13a) is potent AMPK inhibitor with an IC50 value of 0.093 µM. AMPK-IN-6 induces apoptosis and inhibits autophagy. AMPK-IN-6 shows antiproliferative activity. AMPK-IN-6 has the potential for the research of pulmonary arterial hypertension[1].

Applications: COVID-19-immunoregulation

Formula: C18H20FN5O

References: [1]Tan W, et al. A novel pyridine-2-one AMPK inhibitor: Discovery, mechanism, and in vivo evaluation in a hypoxic pulmonary arterial hypertension rat model. Eur J Med Chem. 2025 Jan 12;286:117266.

Molecular Weight: 341.38

Research Area: Cardiovascular Disease

Target: AMPK;Apoptosis;Autophagy

• SKU: MEXHY-172094-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172094-0
• Package Unit: Get quote
• Quantity Unit: STK