Amyloid-β-IN-3, CAS 1603833-56-2

Product Description: Amyloid-β-IN-3 (EX.113) is a selective γ-secretase inhibitor. Amyloid-β-IN-3 inhibits Aβ42 secretion in H4 cells with an EC50 value of 148 nM. Amyloid-β-IN-3 regulates the γ-secretase catalytic activity to decrease Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. Amyloid-β-IN-3 is promising for research of Alzheimer's disease (AD)[1].

Formula: C22H21F2N3O2

References: [1]Indol-amide compounds as beta-amyloid inhbitors. EP2722329A1. 2014-04-23.

CAS Number: 1603833-56-2

Molecular Weight: 397.42

Compound Purity: 99.38

Research Area: Neurological Disease

Target: Amyloid-β;γ-secretase

• SKU: MEXHY-171349-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171349-10
• Package Unit: 10 mg
• Quantity Unit: STK