Product Description: Anti-inflammatory agent 95 (Compound 2e) is an anti-inflammatory agent that exhibits the most potent anti-inflammatory activity in LPS (HY-D1056)-induced RAW 264.7 mouse macrophages.It significantly inhibits the production of NO, with an IC50 of 8.8 μM, and reduces the secretion of TNF-α and IL-1β, with inhibition rates reaching 60% and over 90%, respectively, at a concentration of 100 μM.Anti-inflammatory agent 95 holds promise for research in the field of inflammatory diseases[1].
Formula: C16H21NO4
References: [1]Lu S, et al. Design, synthesis and biological evaluation of Streptazolin analogs as anti-inflammatory agents. Bioorg Med Chem Lett. 2025 Feb 14;120:130139.
Molecular Weight: 291.34
Research Area: Inflammation/Immunology
Target: Interleukin Related;NO Synthase;TNF Receptor