Product Description: Anti-MRSA agent 25 (Compound 10c) is an antibacterial agent with a MIC of 0.25 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 25 exerts its antibacterial activity by inhibiting biofilm formation, disrupting the cell wall (interacting with peptidoglycan and lipoteichoic acids), acting on the cell membrane (causing depolarization, increasing permeability, and disrupting integrity), reducing metabolic activity, interfering with cellular redox homeostasis, and binding to DNA. Anti-MRSA agent 25 is expected to be used in the research of the anti-infection field[1].
Formula: C35H42I2N4
References: [1]Dan W, et al. Synthesis and anti-MRSA activity of quaternized small molecule antimicrobial peptide mimics based on norharmane. Eur J Med Chem. 2025 Jun 5;290:117518.
Molecular Weight: 772.54
Research Area: Infection
Target: Bacterial
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