Anticancer agent 127, CAS 2410953-19-2

Product Description: Anticancer agent 127 (142D6) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 127 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 12 nM, 14 nM, and 9 nM, respectively. Anticancer agent 127 has anticancer effects[1].

Applications: Cancer-programmed cell death

Formula: C26H37FN4O6S

References: [1]Udompholkul P, et al. Characterization of a Potent and Orally Bioavailable Lys-Covalent Inhibitor of Apoptosis Protein (IAP) Antagonist. J Med Chem. 2023 Jun 22;66(12):8159-8169.

CAS Number: 2410953-19-2

Molecular Weight: 552.66

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: IAP

• SKU: MEXHY-155018-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155018-1
• Package Unit: 1 mg
• Quantity Unit: STK