Product Description: Anticancer agent 263 (compound 7) is a potent anticancer agent. Anticancer agent 263 binds to the G-quadruplex DNA (G4) sequence 22-mer Pu22, a mimic of c-Myc DNA. Anticancer agent 263 is a structure modulator, showcasing a significant enhancement in protein α-helix formation and the capability to form supramolecular network. Anticancer agent 263 shows no cytotoxicity[1].
Formula: C13H20N2O6
References: [1]Hayarpi Simonyan, et al. Exploring the binding of c-Myc G-quadruplex and the structural impact of synthetic non-proteinogenic amino acids on serum albumins: implications for potential intrinsic c-Myc-associated anticancer activity and drug delivery systems. Molecular Therapy:Nucleic Acid. 2025./[2]Hayarpi Simonyan, et al. Exploring the binding of c-Myc G-quadruplex and the structural impact of synthetic non-proteinogenic amino acids on serum albumins: implications for potential intrinsic c-Myc-associated anticancer activity and drug delivery systems. Molecular Therapy:Nucleic Acid. 2025.
Molecular Weight: 300.31
Research Area: Cancer
Target: c-Myc