Product Description: Anticonvulsant agent 8 (compound D4) is an anticonvulsant agent that inhibits GABAA currents with ED50 values of 2.23 and 24.60 mg/kg in the maximum electroshock (MES) and pentylenetetrazol (PTZ) tests in mouse models, respectively[1].
Applications: Neuroscience-Neuromodulation
Formula: C15H11N5O
References: [1]Valipour M, et al. Design, synthesis, and structure-activity relationships of five-membered heterocyclic incorporated aryl(alkyl)azoles: From antiproliferative thiazoles to safer anticonvulsant oxadiazoles. Bioorg Chem. 2025 Feb;155:108117.
Molecular Weight: 277.28
Research Area: Neurological Disease
Target: GABA Receptor