Anticonvulsant agent 9

Product Description: Anticonvulsant agent 9 (compound 4f) is an α1β2γ2 GABAA receptors activator. Anticonvulsant agent 9 activatesα1β2γ2 GABAA receptors with an EC50 of 1.24 μM. Anticonvulsant agent 9 inhibits the inactivation of Nav1.2 channels. Anticonvulsant agent 9 exhibits significant anticonvulsant activities[1].

Formula: C22H24N4O2

References: [1]Du T, et al. Design, synthesis and structure-activity relationship of novel 1,2,4-triazolopyrimidin-5-one derivatives targeting GABAA1 and Nav1.2 with antiepileptic activity. Eur J Med Chem. 2025 Mar 15;286:117316.

Molecular Weight: 376.45

Research Area: Neurological Disease

Target: GABA Receptor;Sodium Channel

• SKU: MEXHY-170930-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170930-0
• Package Unit: Get quote
• Quantity Unit: STK