Antimicrobial agent-39

Product Description: Antimicrobial agent-39 (Compound 8i) is an antibiotic that targets 50S ribosomal subunit and inhibits bacterial protein synthesis. Antimicrobial agent-39 disrupts bacterial cell membranes, leads to leakage of cell contents, thereby exhibiting board-spectrum actibacterial activity. Antimicrobial agent-39 targets organic cation transporters (OCTs), accumulates in infected kidneys, thereby ameliorating pyelonephritis in mouse models[1].

Formula: C36H46BrN3O4S

References: [1]Tian L, et al., Kidney Targeting Smart Antibiotic Discovery: Multimechanism Pleuromutilins for Pyelonephritis Therapy. J Med Chem. 2025 Feb 13;68(3):3335-3355.

Molecular Weight: 696.74

Research Area: Infection; Inflammation/Immunology

Target: Antibiotic;Bacterial

• SKU: MEXHY-170993-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170993-0
• Package Unit: Get quote
• Quantity Unit: STK