Product Description: Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic agent. Antiparasitic agent-25 inhibits both parasite invasion and replication ability and has irreversible action against Toxoplasma gondii, significantly reducing the replication rate of Toxoplasma gondii with an IC50 value of 6.33 μM, and demonstrates low cytotoxicity with a CC50 value of 285 μM[1].
Applications: COVID-19-immunoregulation
Formula: C32H29N5O3
References: [1]Deng Y, et al. Design, Synthesis, and Structure-Activity Relationship of 2-(Piperazin-1-yl)quinazolin-4(3H)-one Derivatives as Active Agents against Toxoplasma gondii. J Agric Food Chem. 2025 Mar 12;73(10):6215-6230.
Molecular Weight: 531.60
Research Area: Infection
Target: Parasite