Antiproliferative agent-66

Product Description: Antiproliferative agent-66 (Compound B3) is an antiproliferative agent that induces apoptosis and cell cycle arrest with IC50 values in the range of 2.03-3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblast cells. Antiproliferative agent-66 is also a tubulin polymerization inhibitor with an IC50 of 0.79 µM[1].

Applications: Cancer-programmed cell death

Formula: C18H15N3S

References: [1]Valipour M, et al. Design, synthesis, and structure-activity relationships of five-membered heterocyclic incorporated aryl(alkyl)azoles: From antiproliferative thiazoles to safer anticonvulsant oxadiazoles. Bioorg Chem. 2025 Feb;155:108117.

Molecular Weight: 305.40

Research Area: Cancer

Target: Microtubule/Tubulin

• SKU: MEXHY-170834-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170834-0
• Package Unit: Get quote
• Quantity Unit: STK