Product Description: Antitumor agent-198 (Compound A3) exhibits cytotoxicity in head and neck squamous cell carcinoma (HNSCC) cells, that inhibits the proliferation of CAL27, HN6, HN30, SCC9 and SCC25 with IC50 of 4 nM-77 nM. Antitumor agent-198 inhibits the HNSCC cell migration, arrests the cell cycle, and induces apoptosis[1].
Formula: C32H28O12S
References: [1]Tang Y, et al., Synthesis and pharmacological evaluation of natural product diphyllin derivatives against head and neck squamous cell carcinoma. Eur J Med Chem. 2025 Mar 5;285:117215.
Molecular Weight: 636.62
Research Area: Cancer
Target: Apoptosis