ARB-272572, CAS 2368182-63-0

Product Description: ARB-272572 is an oral effective small molecule PD-L1 inhibitor, with an IC50 value of 400 pM. ARB-272572 has research significance in tumors and chronic viral infections[1][2].

Applications: Cancer-programmed cell death

Formula: C32H36N6O4

References: [1]Park JJ, et al. Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1. Nat Commun. 2021 Feb 22;12(1):1222. /[2]Zhijie Wang, et al. Reducing PD-L1 Expression by Degraders and Downregulators as a Novel Strategy to Target the PD-1/PD-L1 Pathway. J Med Chem. 2024 Apr 25;67(8):6027-6043.

CAS Number: 2368182-63-0

Molecular Weight: 568.67

Compound Purity: 99.85

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: PD-1/PD-L1

• SKU: MEXHY-142221-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-142221-100
• Package Unit: 100 mg
• Quantity Unit: STK