Arimoclomol (citrate), CAS 368860-21-3

Arimoclomol (citrate), CAS 368860-21-3
SKU
MEXHY-106443B-10.1
Packaging Unit
10 mM/1 ml
Manufacturer
MedChemExpress

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Product Description: Arimoclomol citrate (BRX-220 citrate) is an orally active co-inducer of heat shock proteins (HSP)[1]. Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system[2]. Arimoclomol citrate can be used for the study of Niemann–Pick disease type C.

Applications: Metabolism-protein/nucleotide metabolism

Formula: C20H28ClN3O10

References: [1]Rakonczay Z Jr, et al. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92./[2]Phukan J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Jul;13(7):482-96.

CAS Number: 368860-21-3

Molecular Weight: 505.90

Compound Purity: 99.76

Research Area: Metabolic Disease; Inflammation/Immunology; Neurological Disease

Solubility: DMSO : 35 mg/mL (ultrasonic)

Target: HSP
More Information
SKU MEXHY-106443B-10.1
Manufacturer MedChemExpress
Manufacturer SKU HY-106443B-10.1
Package Unit 10 mM/1 ml
Quantity Unit STK
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