ATG16L1 stabilizer-1

Product Description: ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent ATG16L1 stabilizer that promotes cellular Autophagy. ATG16L1 stabilizer-1 inhibits ATG16L1 with an EC50 of 12.1 μM in the presence or absence of FKBP12. ATG16L1 stabilizer-1 alone induces GFP-LC3 puncta formation to a small extent with an EC50 of 12.0 μM[1].

Formula: C45H62N14O5S

References: [1]Tan ZY, et al. Development of an FKBP12-recruiting chemical-induced proximity DNA-encoded library and its application to discover an autophagy potentiator. Cell Chem Biol. 2024 Dec 30:S2451-9456(24)00491-4.

Molecular Weight: 911.13

Research Area: Inflammation/Immunology

Target: Autophagy

• SKU: MEXHY-170998-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170998-0
• Package Unit: Get quote
• Quantity Unit: STK