β-S-ARCA (triammonium)

Product Description: β-S-ARCA (triammonium) is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNA incorporating β-S-ARCA (triammonium) can prolong cellular half-life and increase protein expression. β-S-ARCA (triammonium) can be used in research of mRNA-based anti-cancer vaccines[1].

Applications: Cancer-programmed cell death

Formula: C22H40N13O17P3S

References: [1]Warminski M, et al. Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect. ACS Chem Biol. 2021 Feb 19;16(2):334-343.

Molecular Weight: 883.62

Compound Purity: 99.48

Research Area: Cancer

Solubility: H2O : 50 mg/mL (ultrasonic)

Target: DNA/RNA Synthesis

• SKU: MEXHY-145969A-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145969A-50
• Package Unit: 50 mg
• Quantity Unit: STK