BAY-678 (racemate), CAS 675103-35-2

Product Description: BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

Applications: Neuroscience-Neuromodulation

Formula: C20H15F3N4O2

References: [1]von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.

CAS Number: 675103-35-2

Molecular Weight: 400.35

Compound Purity: 98.30

Research Area: Inflammation/Immunology

Solubility: DMSO : ≥ 150 mg/mL

Target: Elastase

• SKU: MEXHY-111515-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-111515-25
• Package Unit: 25 mg
• Quantity Unit: STK