BGC4

Product Description: BGC4 is a biphenyl-based gold(III) complex. BGC4 inhibits human recombinant thioredoxin reductase (TrxR) with an IC50 of 10.7 μM, exhibits cytotoxicity (IC50 for MDA-MB-231 is 5.4 μM), and induces apoptosis. BGC4 exhibits antitumor efficacy in mouse models[1].

Applications: Cancer-programmed cell death

Formula: C30H33AuClF3N3

References: [1]Remadna E, et al., Synthesis and Biological Evaluation of a New Biphenyl-Based Organogold(III) Complex with In Vitro and In Vivo Anticancer Activity. J Med Chem. 2025 Jan 23;68(2):1755-1771.

Molecular Weight: 725.02

Research Area: Cancer

Target: Apoptosis;TrxR

• SKU: MEXHY-172115-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172115-0
• Package Unit: Get quote
• Quantity Unit: STK