BIO-2007817

Product Description: BIO-2007817 is a Parkin positive allosteric modulators (PAMs). BIO-2007817 enhances the activity of wildtype Parkin. BIO-2007817 stimulates Parkin (an E3 ligase)autoubiquitination and induces the appearance of monoubiquitinated forms of Miro1 (EC50: 0.17 μM)[1].

Applications: Neuroscience-Neuromodulation

Formula: C32H36N6O3

References: [1]Shlevkov E, et al. Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase. iScience. 2021 Dec 18;25(1):103650.

Molecular Weight: 552.67

Compound Purity: 99.35

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: E1/E2/E3 Enzyme;PINK1/Parkin

• SKU: MEXHY-169329-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-169329-25
• Package Unit: 25 mg
• Quantity Unit: STK