Product Description: BLINK11 is a BBB-penetrant CDK5 inhibitor. BLINK11 lowers CDK5 activity for both complexes CDK5/p35 (IC50 = 17.09 nM) and CDK5/p25 (IC50 = 14.69 nM). BLINK11 offers anti-diabetic and neuroprotective benefits. BLINK11 lowers blood glucose, enhances cognition, and reduces neurodegeneration in T2D mice[1].
Applications: Neuroscience-Neuromodulation
Formula: C25H22Cl3N3O4
References: [1]Paul S, et al,. A Cdk5 inhibitor restores cognitive function and alleviates type 2 diabetes in mice. iScience. 2025 Mar 11;28(4):112200.
Molecular Weight: 534.82
Research Area: Neurological Disease
Target: CDK