Product Description: BLINK15 is a BBB-penetrant CDK5 inhibitor. BLINK15 lowers CDK5 activity for both complexes CDK5/p35 (IC50 = 29.34 nM) and CDK5/p25 (IC50 = 12.08 nM). BLINK15 offers anti-diabetic and neuroprotective benefits. BLINK15 lowers blood glucose, enhances cognition, and reduces neurodegeneration in T2D mice[1].
Applications: Neuroscience-Neuromodulation
Formula: C24H19BrN2O6
References: [1]Paul S, et al,. A Cdk5 inhibitor restores cognitive function and alleviates type 2 diabetes in mice. iScience. 2025 Mar 11;28(4):112200.
Molecular Weight: 511.32
Research Area: Neurological Disease
Target: CDK