BM212 (Standard), CAS 146204-42-4

Product Description: BM212 (Standard) is the analytical standard of BM212. This product is intended for research and analytical applications. BM212 is a potent Mycobacterial membrane protein Large 3 (MmpL3) inhibitor. BM212 has strong bactericidal activity against both M. tuberculosis and some nontuberculosis mycobacteria. BM212 exhibits antimycobacterial activity against M. tuberculosis H37Rv with an MIC of 5 µM[1][2].

Formula: C23H25Cl2N3

References: [1]Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2)/[2]Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7./[3]Albertus Viljoen, et al. Fast chemical force microscopy demonstrates that glycopeptidolipids define nanodomains of varying hydrophobicity on mycobacteria. Nanoscale Horiz. 2020 Jun 1;5(6):944-953./[4]Delia Deidda, et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.

CAS Number: 146204-42-4

Molecular Weight: 414.37

Research Area: Infection

Target: Bacterial;Reference Standards

• SKU: MEXHY-100725R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100725R-0
• Package Unit: Get quote
• Quantity Unit: STK