BMPR2-IN-1

Product Description: BMPR2-IN-1 (Compound 8a) is a BMPR2 inhibitor with an IC50 of 506 nM and a KD of 83.5 nM. BMPR2-IN-1 can be used for research of pulmonary arterial hypertension, Alzheimer’s disease and cancer[1].

Applications: Cancer-Kinase/protease

Formula: C16H15N7O

References: [1]Amrhein JA, et al. Design and Synthesis of Pyrazole-Based Macrocyclic Kinase Inhibitors Targeting BMPR2. ACS Med Chem Lett. 2023 May 30;14(6):833-840.

Molecular Weight: 321.34

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: TGF-β Receptor

• SKU: MEXHY-154970-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-154970-0
• Package Unit: Get quote
• Quantity Unit: STK