Product Description: BMS-191095 hydrochloride is a mitochondrial KATP channel opener. BMS-191095 hydrochloride can protect the myocardium without causing vasodilation or affecting electrophysiology, by prolonging the contraction time during ischemia, improving contractile function after reperfusion, and reducing lactate dehydrogenase (LDHM) release, thereby exerting its cardioprotective effects[1].
Formula: C22H22Cl2N4O2
References: [1]Grover GJ, et al. Pharmacologic profile of the selective mitochondrial-K(ATP) opener BMS-191095 for treatment of acute myocardial ischemia. Cardiovasc Drug Rev. 2002 Summer;20(2):121-36.
CAS Number: 166095-95-0
Molecular Weight: 445.34
Research Area: Cardiovascular Disease
Target: Lactate Dehydrogenase;Potassium Channel