Product Description: BRD4 Inhibitor-27 (compound 6) is a BRD4 inhibitor with IC50 of 9.6 and 11.3 μM for BRD4 BD1 and BRD4 BD2, respectively. BRD4 Inhibitor-27 has the potential to study cancer[1].
Applications: Cancer-programmed cell death
Formula: C16H13F3N6
References: [1]Kim JH, et al. Crystal structure of [1,2,4] triazolo[4,3- b ]pyridazine derivatives as BRD4 bromodomain inhibitors and structure–activity relationship study . Sci Rep 13, 10805 (2023).
CAS Number: 930039-92-2
Molecular Weight: 346.31
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Epigenetic Reader Domain