BuChE-IN-16

Product Description: BuChE-IN-16 (Compound 6a) is an orally active, BBB-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. BuChE-IN-16 has anti-inflammatory and neuroprotective effects. BuChE-IN-16 can improve the cognitive function of zebrafish with Alzheimer's disease (AD) and alleviate memory impairment in mice induced by Scopolamine (HY-N0296). BuChE-IN-16 can be used for the research of AD[1].

Formula: C16H22N2O3

References: [1]Li Y, et al. Development of novel rivastigmine derivatives as selective BuChE inhibitors for the treatment of AD. Bioorg Chem. 2025 Feb 6;157:108245.

Molecular Weight: 290.36

Research Area: Neurological Disease

Target: Cholinesterase (ChE)

• SKU: MEXHY-170976-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170976-0
• Package Unit: Get quote
• Quantity Unit: STK