Product Description: CAMK1D-IN-1 (compound I) is an inhibitor of CAMK1D, targeting cytotoxic T lymphocyte (CTL)-resistant tumor cells. CAMK1D impairs CTL-induced death receptor signaling and apoptosis by inhibiting caspases, making it a key and effective target for PD-L1-refractory tumors[1].
Applications: Cancer-programmed cell death
Formula: C18H19N5
References: [1]Valentina Volpin, et al. Intracellular kinase associated with resistance against t-cell mediated cytotoxicity, and uses thereof. WO2021229105A1. 2021-05-17
CAS Number: 404828-08-6
Molecular Weight: 305.38
Compound Purity: 99.06
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: CaMK