Casein kinase 1δ-IN-27, CAS 1095706-65-2

Product Description: Casein kinase 1δ-IN-27 (Compound 8) is the inhibitor for casein kinase 1 that inhibits CK1α, CK1δ, CK1ε, and p38α with IC50s of 22, 16.5, 9.41 and 14.8 nM, respectively. Casein kinase 1δ-IN-27 inhibits the DUX4 expression with an IC50 of 10 nM[1].

Formula: C21H19FN6

References: [1]Maeyer JD, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717

CAS Number: 1095706-65-2

Molecular Weight: 374.41

Research Area: Cancer

Target: Casein Kinase;p38 MAPK

• SKU: MEXHY-171277-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171277-0
• Package Unit: Get quote
• Quantity Unit: STK