Product Description: Casein kinase 1δ-IN-31 (Compound 16) is the inhibitor for casein kinase (CK) that inhibits CK1α, CK1δ, and p38α with IC50s of 196, 17, and 18 nM, respectively. Casein kinase 1δ-IN-31 inhibits Double Homeobox 4 (DUX4) with IC50 of 1200 nM[1].
Applications: COVID-19-anti-virus
Formula: C17H13FN4
References: [1]Maeyer JD, et al., Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717
CAS Number: 2567490-30-4
Molecular Weight: 292.31
Research Area: Inflammation/Immunology
Target: Casein Kinase;p38 MAPK