Cbl-b-IN-28

Product Description: Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. Cbl-b-IN-28 promotes the secretion of cytokines such as IL-2 and enhances the function of immune cells by regulating the phosphorylation levels of key proteins in the T-cell receptor signaling pathway. Cbl-b-IN-28 can be used in research in the field of cancer immunology[1].

Formula: C29H33F3N6O

References: [1]Zhang Y, et al. Rational design, optimization, and biological evaluation of novel pyrrolo-pyridone derivatives as potent and orally active Cbl-b inhibitors. Eur J Med Chem. 2025 Jun 5;290:117488.

Molecular Weight: 538.61

Research Area: Cancer; Inflammation/Immunology

Target: E1/E2/E3 Enzyme;Interleukin Related

• SKU: MEXHY-173311-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173311-0
• Package Unit: Get quote
• Quantity Unit: STK