CD38 inhibitor 3, CAS 2857868-82-5

Product Description: CD38 inhibitor 3 (compound 1) is the orally active inhibitor for CD38 (IC50=11 nM). CD38 inhibitor 3 increases intracellular NAD+ levels, activates the Nrf2 signaling pathway, and promotes mitochondrial biogenesis. CD38 inhibitor 3 improves muscle function[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C16H14F3N7O3

References: [1]Li Y, et al. Discovery of a First-in-Class CD38 Inhibitor for the Treatment of Mitochondrial Myopathy. J Med Chem. 2023 Sep 11.. .

CAS Number: 2857868-82-5

Molecular Weight: 409.32

Compound Purity: 99.16

Research Area: Metabolic Disease

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: CD38

• SKU: MEXHY-156120-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-156120-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK