CDD-1431, CAS 3034216-31-1

CDD-1431, CAS 3034216-31-1
SKU
MEXHY-171249-0
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MedChemExpress

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Product Description: CDD-1431 is a low-nanomolar selective kinase inhibitors of BMPR2, with Kiapp value of 20.6 nM. CDD-1431 suppresses BRE-reporter activity, with an IC50 of 4.87 μM. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation[1].

Formula: C33H38N8O5S

References: [1]Modukuri RK, et al. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 Feb 9;66(3):2143-2160.

CAS Number: 3034216-31-1

Molecular Weight: 658.77

Research Area: Endocrinology; Cardiovascular Disease

Target: TGF-β Receptor
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SKU MEXHY-171249-0
Manufacturer MedChemExpress
Manufacturer SKU HY-171249-0
Package Unit Get quote
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