CDK2 degrader 1, CAS 3036604-59-5

Product Description: CDK2 degrader 1 (Compound 3) is an orally active cyclin-dependent kinase 2 (CDK2) degrader based on PROTAC technology. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the CDK2. CDK2 degrader 1 is used in the research of a wide range of cancers (Red: spiro[3.3]heptan-2- ylmethyl carbonochloridate; Blue: N,N-diisopropylethylamine; Black: linker)[1].

Applications: Cancer-Kinase/protease

Formula: C23H27F2N3O4

References: [1]Fasching B, et al. Compounds that mediate protein degradation and methods of use thereof[J]. US patent WO2023069700A1, 2022.

CAS Number: 3036604-59-5

Molecular Weight: 447.47

Compound Purity: 99.74

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: CDK;PROTACs

• SKU: MEXHY-163814-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163814-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK