CDKL5/GSK3-IN-1, CAS 844442-32-6

Product Description: CDKL5/GSK3-IN-1 (Compound 2) is a potent and selectivity chemical probe for CDKL5/GSK3.CDKL5/GSK3-IN-1 has potent inhibition of CDKL5 and GSK3α/β, with IC50 values of 4.6, 24 and 9.5 nM for CDKL5, GSK3β and GSK3α, respectively, in the NanoBRET assay. CDKL5/GSK3-IN-1 can be used for the research of CNS diseases[1].

Formula: C16H17F2N5O2

References: [1]Ong HW, et al. A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective. bioRxiv [Preprint]. 2023 Feb 10:2023.02.09.527935.

CAS Number: 844442-32-6

Molecular Weight: 349.34

Compound Purity: 98.72

Research Area: Neurological Disease

Solubility: DMSO : 20 mg/mL (ultrasonic)

Target: GSK-3

• SKU: MEXHY-172118-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172118-50
• Package Unit: 50 mg
• Quantity Unit: STK