CGK012, CAS 2044497-76-7

Product Description: CKG012 is an inhibitor for Wnt/βcatenin signaling pathway. CGK012 inhibits release of HMGB1 and transcription of β-catenin, exhibits attenuating activities against cecal ligation and puncture (CLP)-induced sepsis and multiple myeloma cancer[1][2].

Applications: COVID-19-immunoregulation

Formula: C20H23NO5

References: [1]Park YJ, et al., Antiseptic Functions of CGK012 against HMGB1-Mediated Septic Responses. Int J Mol Sci. 2024 Mar 4;25(5):2976. /[2]Choi PJ,et al., Anti-proliferative activity of CGK012 against multiple myeloma cells via Wnt/β-catenin signaling attenuation. Leuk Res. 2017 Sep;60:103-108.

CAS Number: 2044497-76-7

Molecular Weight: 357.40

Compound Purity: 99.96

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : ≥ 25 mg/mL

Target: Wnt;β-catenin

• SKU: MEXHY-163409-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163409-10
• Package Unit: 10 mg
• Quantity Unit: STK