Product Description: CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research[1].
Applications: Neuroscience-Neurodegeneration
Formula: C15H10BrFO
References: [1]Thomas Parambi DG, et al. Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study. Comput Biol Chem. 2023 Aug;105:107899.
CAS Number: 98991-32-3
Molecular Weight: 305.14
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Monoamine Oxidase;Reactive Oxygen Species