Chloroquine (dihydrochloride), CAS 3545-67-3

Chloroquine (dihydrochloride), CAS 3545-67-3
SKU
MEXHY-17589B-10
Packaging Unit
10 mg
Manufacturer
MedChemExpress

Availability: loading...
Price is loading...
Product Description: Chloroquine dihydrochloride is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine dihydrochloride is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine dihydrochloride is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM)[1][2][3][4].

Applications: COVID-19-anti-virus

Formula: C18H28Cl3N3

Citations: Acta Pharmacol Sin. 2020 Aug 11. /Front Cell Dev Biol. 2021 Jan 14./Research Square Preprint. 2021 Aug./ACS Nano. 2023 Nov 15./ACS Nano. 2024 Aug 28./ACS Nano. 2024 Jan 22./ACS Pharmacol Transl Sci. 2023 Dec 12./ACS Pharmacol Transl Sci. 2023 Sep 1./Acta Biochim Biophys Sin (Shanghai). 2024 Nov 22./Acta Pharm Sin B. 17 September 2021./Acta Pharm Sin B. 2023 May 29./Acta Pharm Sin B. 2024 Aug 8./Acta Pharm Sin B. 2024 Dec 31./Acta Pharm Sin B. 21 July 2021./Acta Pharmacol Sin. 2021 Feb 19./Acta Pharmacol Sin. 2022 Jul;43(7):1793-1802./Acta Pharmacol Sin. 2025 Feb 21./Adv Funct Mater. 2020, 2004940./Adv Sci (Weinh). 2023 Dec 12:e2305620./Adv Sci (Weinh). 2023 Dec;10(36):e2303484./Adv Sci (Weinh). 2023 Jul 10;e2301088./Adv Sci (Weinh). 2023 Nov 16:e2306535./Adv Sci (Weinh). 2023 Oct;10(28):e2302130./Adv Sci (Weinh). 2024 Aug 8:e2406633./Adv Sci (Weinh). 2024 Dec 16:e2411479./Adv Sci (Weinh). 2024 Dec 25:e2409416./Adv Sci (Weinh). 2024 Dec 25:e2413122./Adv Sci (Weinh). 2024 Dec 31:e2411943./Adv Sci (Weinh). 2024 Jun 5:e2402030./Adv Sci (Weinh). 2024 May 13:e2400790./Adv Sci (Weinh). 2024 May 2:e2309907./Adv Sci (Weinh). 2024 Nov 5:e2410285./Adv Sci (Weinh). 2024 Sep 18:e2407132./Adv Sci (Weinh). 2025 Jan 13:e2409086./Adv Sci (Weinh). 2025 Jan 21:e2407942./Adv Sci (Weinh). 2025 Jan 21:e2413990./Adv Sci (Weinh). 2025 Mar 5:e2415041./Am J Cancer Res. 2023 Aug 15;13(8):3705-3720./Am J Cancer Res. 2023 Feb 28./Am J Cancer Res. 2023 Nov 15;13(11):5590-5609./Am J Reprod Immunol. 2024 Feb;91(2):e13820./Am J Transl Res. 2023 Aug 15;15(8):5129-5144./Animals (Basel). 2024 Oct 6;14(19):2876./Antioxid Redox Signal. 2023 Jan 5./Antioxid Redox Signal. 2024 May 8./Antioxidants (Basel). 2024 Jan 31;13(2):183./Antioxidants (Basel). 2024 Jul 9./Antioxidants (Basel). 2024 Nov 24./Antioxidants (Basel). 2024 Oct 21;13(10):1272./Antiviral Res. 2023 May 6;105621./Apoptosis. 2024 May 14./Arch Biochem Biophys. 2024 Oct 10:110180./Arch Microbiol. 2025 Feb 10;207(3):54./Arch Physiol Biochem. 2024 Sep 3:1-10./Autophagy. 2021 Apr 23;1-22./Autophagy. 2021 Dec 29;1-13./Autophagy. 2021 Dec 8;1-23./Autophagy. 2021 Mar 22;1-17./Autophagy. 2021 Nov 25;1-21./Autophagy. 2022 Aug 1;1-19./Autophagy. 2022 Mar 22;1-21./Autophagy. 2022 Mar 3;1-17./Autophagy. 2022 Nov 30;1-18./Autophagy. 2024 Aug 22./Autophagy. 2024 Dec 17:1-20./Autophagy. 2024 Dec 5./Autophagy. 2024 Jun 24./Autophagy. 2024 May 5./Autophagy. 2024 Oct 16:1-17./Autophagy. 2024 Oct 30./Autophagy. 2025 Feb 14:1-17./Autophagy. 2025 Feb 25./Autophagy. 2025 Feb 4./Autophagy. 2025 Mar 18./Bioact Mater. 2021 Nov 19;13:23-36./Biochem Biophys Res Commun. 2 March 2022./Biochem Biophys Res Commun. 2020 Dec 10;533(3):474-480./Biochem Biophys Res Commun. 2020 Jul 12;528(1):105-111./Biochem Biophys Res Commun. 2021 Mar 4;550:15-21./Biochem Biophys Res Commun. 2023 Mar 21;657:69-79./Biochem Biophys Res Commun. 2024 May 14, 708, 149815./Biochem Biophys Res Commun. 27 July 2021./Biochem Genet. 2024 Jun 6./Biochem Pharmacol. 2021 May 3;114588./Biochem Pharmacol. 2023 Apr 18;115554./Biochem Pharmacol. 2023 May 30;115632./Biochem Pharmacol. 2023 Oct 18:115870./Biochem Pharmacol. 2024 Jun 15:116373./Biochem Pharmacol. 2025 Feb 28:116843./Biochem Pharmacol. 2025 Jan 29:116788./Biochim Biophys Acta Mol Basis Dis. 2024 Jan 2:167012./Biochim Biophys Acta Mol Basis Dis. 2025 Jan 11./Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Jul 9;159364./Biochim Biophys Acta Mol Cell Res. 2021 Jun 1;119074./Biochim Biophys Acta Mol Cell Res. 2022: 119411./Biochim Biophys Acta Mol Cell Res. 2024 Mar 22;1871(4):119712./Biol Open. 2020 Nov 12;9(11):bio053298./Biomaterials. 2024 Dec 27:317:123062./Biomaterials. 2025 Jan 3:317:123091./Biomed Pharmacother. 2020 Dec 31;135:111034./Biomed Pharmacother. 2020 Dec;132:110898./Biomed Pharmacother. 2021 Jan;133:111023./Biomed Pharmacother. 2022 Jun;150:112927./Biomed Pharmacother. 2023 Dec 14:170:115867./Biomed Pharmacother. 2023 Feb 3;160:114340./Biomed Pharmacother. 2023 Jun 8;164:114980./Biomed Pharmacother. 2023 Mar 18;161:114560./Biomed Pharmacother. 2024 Apr 25:175:116614./Biomed Pharmacother. 2024 Jun 14:177:116918./Biomedicines. 2023 Mar 21;11(3):973./Biomolecules. 2024 May 23./Biomolecules. 2025 Feb 10./Bioorg Chem. 20 August 2023, 106795/Bioorg Med Chem. 2023 Mar 7;82:117235./Bioresources and Bioprocessing. 8, 4 (2021)./bioRxiv. 2023 Feb 23./bioRxiv. 2023 Oct 20:2023.10.19.563158./bioRxiv. 2023 Oct 4./bioRxiv. 2024 Apr 10./bioRxiv. 2024 Apr 4./bioRxiv. 2024 August 30./bioRxiv. 2024 Feb 16./bioRxiv. 2024 Feb 19./bioRxiv. 2024 Feb 7./bioRxiv. 2024 Jul 27:2024.07.25.605164./bioRxiv. 2025 February 08./Biosens Bioelectron. 2025 Jan 25:274:117184./BMC Complement Med Ther. 2022 Apr 6;22(1):100./BMC Med Genomics. 2024 Jan 26;17(1):36./BMC Mol Cell Biol. 2023 Mar 3;24(1):7./BMC Pharmacol Toxicol. 2024 May 23;25(1):33./Bone. 2021 Nov 20;116262./Bone. 2024 Nov 29:192:117348./Br J Pharmacol. 2024 Jun 16./Br J Pharmacol. 2024 May 7./Cancer Biol Ther. 2023 Dec 31;24(1):2230641./Cancer Cell Int. 2024 Feb 19;24(1):79./Cancer Cell Int. 2024 Jun 3;24(1):194./Cancer Commun (Lond). 2023 Apr 2./Cancer Gene Ther. 2023 Feb 13./Cancer Immunol Res. 2022 May 17;canimm.0652.2021./Cancer Lett. 2021 Feb 1;498:54-69./Cancer Lett. 2021 Oct 28;519:2-19./Cancer Lett. 2024 Jun 14:597:217005./Cancer Lett. 2024 Jun 28:217092./Cancer Med. 2024 Jun;13(11):e7382./Cancers (Basel). 2021 Jul 11;13(14):3467./Cancers (Basel). 2022 May 9;14(9):2338./Cancers (Basel). 2023 Apr 23, 15(9), 2427./Cancers (Basel). 2024 Sep 26;16(19):3269./Carbohydr Polym. 2023 Jun 9, 121108./Cell Biosci. 2022 Aug 21;12(1):135./Cell Biosci. 2025 Feb 5;15(1):14./Cell Commun Signal. 2023 Feb 20;21(1):39./Cell Commun Signal. 2024 May 3;22(1):254./Cell Commun Signal. 2024 Oct 11;22(1):488./Cell Cycle. 2020 Sep;19(17):2216-2225./Cell Death Differ. 2022 Jun 22./Cell Death Differ. 2023 Jun 15./Cell Death Differ. 2023 May 4./Cell Death Differ. 2023 Nov 25./Cell Death Differ. 2024 Aug 14./Cell Death Differ. 2024 Mar 15./Cell Death Differ. 2025 Jan 18./Cell Death Differ. 2025 Jan 28./Cell Death Dis. 2020 Mar 13;11(3):183./Cell Death Dis. 2022 Apr 22;13(4):396./Cell Death Dis. 2022 Aug 18;13(8):721./Cell Death Dis. 2022 Dec 12;13(12):1034./Cell Death Dis. 2022 Jul 15;13(7):615./Cell Death Dis. 2022 Jul 28;13(7):653./Cell Death Dis. 2022 Mar 30;13(3):283./Cell Death Dis. 2022 May 20;13(5):479./Cell Death Dis. 2022 Nov 28;13(11):1007./Cell Death Dis. 2022 Sep 25;13(8):728./Cell Death Dis. 2022 Sep 26;13(9):824./Cell Death Dis. 2023 Mar 11;14(3):193./Cell Death Dis. 2023 Mar 25;14(3):211./Cell Death Dis. 2023 Oct 23;14(10):695./Cell Death Dis. 2023 Oct 9;14(10):657./Cell Death Dis. 2023 Sep 4;14(9):588./Cell Death Dis. 2024 Nov 1;15(11):786./Cell Death Dis. 2024 Oct 2;15(10):725./Cell Death Dis. 2024 Sep 6;15(9):655./Cell Death Dis. 2025 Mar 12;16(1):170./Cell Death Discov. 2021 Dec 14;7(1):389./Cell Death Discov. 2021 Sep 20;7(1):254./Cell Death Discov. 2022 Feb 11;8(1):59./Cell Death Discov. 2023 Aug 18;9(1):302./Cell Death Discov. 2023 Jan 21;9(1):15./Cell Death Discov. 2023 Nov 18;9(1):419./Cell Death Discov. 2024 Jul 19;10(1):329./Cell Mol Gastroenterol Hepatol. 2022 Oct 13;S2352-345X(22)00216-8./Cell Mol Gastroenterol Hepatol. 2022 Oct 21;S2352-345X(22)00222-3./Cell Mol Immunol. 2025 Feb 5./Cell Mol Immunol. 2025 Mar 4./Cell Mol Life Sci. 2023 Oct 13;80(11):325./Cell Oncol (Dordr). 2024 Dec 24./Cell Prolif. 2021 Oct 20;e13136./Cell Rep Med. 2024 Jan 11:101357./Cell Rep Med. 2025 Jan 27:101928./Cell Rep Methods. 2023 Oct 23;3(10):100599./Cell Rep. 2022 Apr 12;39(2):110656./Cell Rep. 2022 Jul 19;40(3):111077./Cell Rep. 2023 Jan 31;42(1):112002./Cell Rep. 2023 Mar./Cell Rep. 2023 Nov 10;42(11):113417./Cell Rep. 2024 May 15;43(5):114237./Cell Res. 2023 Jul 17./Cell Signal. 2022 Oct 18;110500./Cell Signal. 2024 Aug 7:111342./Cell Signal. 2025 Feb 13:111658./Cell Signal. 2025 Feb 15:111669./Cell Signal. 2025 Jan 3:111583./Cells. 2022 Sep 25;11(19):2987./Cells. 2022, 11(12), 1870./Cells. 2022, 11(17), 2706./Chem Biol Interact. 2023 Feb 21;110408./Chem Biol Interact. 2023 Nov 9:110794./Chem Biol Interact. 386, 1 December 2023, 110785/Chem Eng J. 2023 Nov 1, 475, 146449./Chem Eng J. 2024 Apr 15, 486 150125./ChemMedChem. 2023 Jun 16;e202300114./Chemosphere. 2021, 130034./Chin J Integr Med. 2025 Mar 7./Chin Med. 2021 Nov 24;16(1):123./Chin Med. 2024 Apr 8;19(1):59./Clin Epigenetics. 2023 Jan 17;15(1):10./Clin Exp Dermatol. 2022 Jun 22./Clin Immunol. 2023 Jan 20;247:109238./Clin Transl Med. 2023 Mar;13(3):e1229./Clin Transl Med. 2024 Oct;14(10):e70038./CNS Neurosci Ther. 2023 Aug 29./Commun Biol. 2022 Jun 29;5(1):641./Commun Biol. 2024 Nov 5;7(1):1438./Connect Tissue Res. 2025 Feb 11:1-14./Curr Eye Res. 2024 Apr 5:1-10./Curr Eye Res. 2024 Sep 4:1-8./Diabetes. 2021 Oct 21;db210240./Drug Chem Toxicol. 2021 Sep 22;1-12./Drug Des Dev Ther. 2021 Aug 21;15:3643-3659./Drug Des Devel Ther. 2020 May 18;14:1897-1908./Drug Resist Updat. 2025 Feb 28./Ecotoxicol Environ Saf. 2023 Mar 14;255:114725./Ecotoxicol Environ Saf. 2023 Sep 22;265:115505./Ecotoxicol Environ Saf. 2024 Aug 13:284:116854./Ecotoxicol Environ Saf. 2024 Jul 1:279:116446./Ecotoxicol Environ Saf. 2024 Oct 19:286:117225./Ecotoxicol Environ Saf. 25 December 2021, 113028./EMBO Mol Med. 2023 Jan 18;e16235./EMBO Mol Med. 2025 Feb 28./EMBO Rep. 2022 Apr 11;e53932./EMBO Rep. 2024 Sep 16./EMBO Rep. 2024 Sep 6./Emerg Microbes Infect. 2023 Oct 26:2276336./Endocrine. 2020 Dec;70(3):526-537./Environ Int. 2024 Aug:190:108897./Environ Int. 2024 Feb:184:108480./Environ Pollut. 2022: 120627./Environ Pollut. 2024 Mar 8:123740./Environ Toxicol. 2021 Nov 29./Environ Toxicol. 2023 Jul 19./Eur J Med Res. 2024 Dec 20;29(1):611./Eur J Pharmacol. 2020 Nov 5;886:173526./Eur J Pharmacol. 2022 Feb 11;920:174822./Eur J Pharmacol. 2023 Aug 10;175982./Eur J Pharmacol. 2023 Jun 26;175863./Evid Based Complement Alternat Med. 2021 Sep 16;2021:8548380./Evid Based Complement Alternat Med. 2022./Exp Cell Res. 2023 Jan 7;113469./Exp Cell Res. 2024 May 13:114094./Exp Mol Med. 2022 Sep 21./Exp Ther Med. July 5, 2021./Exp Ther Med. September 16, 2021./FASEB J. 2022 Dec;36(12):e22672./FASEB J. 2022 Jun;36(6):e22359./FEBS J. 2024 Oct 21./Fish Shellfish Immunol. 2023 Mar 8;135:108672./Fish Shellfish Immunol. 2023 Oct 5:142:109145./Food Biosci. 2024 Oct./Food Biosci. 2025 Mar./Food Chem Toxicol. 2023 Apr 18;113793./Food Funct. 2021 Mar 31./Food Funct. 2022 May 23;13(10):5559-5570./Food Funct. 2023 Apr 17./Free Radic Biol Med. 2021 Apr 22;S0891-5849(21)00265-3./Free Radic Biol Med. 2022 Aug 5;S0891-5849(22)00508-1./Free Radic Biol Med. 2022 Mar;181:82-97./Free Radic Biol Med. 2022./Free Radic Biol Med. 2023 Apr 10;S0891-5849(23)00373-8./Free Radic Biol Med. 2023 Aug 25;S0891-5849(23)00605-6./Free Radic Biol Med. 2023 Dec 14:211:127-144./Free Radic Biol Med. 2024 Aug 10:S0891-5849(24)00582-3./Free Radic Biol Med. 2024 Jan 10:S0891-5849(24)00011-X./Free Radic Biol Med. 2025 Feb 11:S0891-5849(25)00085-1./Free Radic Biol Med. 2025 Mar 1:S0891-5849(25)00130-3./Front Biosci (Landmark Ed). 2023 Dec 1, 28(12), 325./Front Cell Dev Biol. 2021 Oct 22;9:756743./Front Cell Dev Biol. 2021 Oct 6;9:734818./Front Cell Dev Biol. 30 March 2021./Front Immunol. 2021 Jul./Front Immunol. 2021 May 18;12:662989./Front Immunol. 2022./Front Immunol. 2024 May 10./Front Mol Biosci. 22 July 2022./Front Neurosci. 2022 Jun 7;16:901688./Front Oncol. 2021 Jun 18;11:656608./Front Pharmacol. 16 July 2021./Front Pharmacol. 19 July 2021./Front Pharmacol. 2021 Jul 9;12:684915./Front Pharmacol. 2022 Jan 24;13:834296./Front Pharmacol. 2022 Sep 16;13:977622./Front Pharmacol. 2025 Jan 23:16:1504683./Front Pharmacol. 22 July 2022./Fundam Res. 2023 Apr 7./Gene Ther. 2021 Aug 20./Genes Dis. 2020 Nov 21;8(6):867-881./Gut Microbes. 2024 Jan-Dec;16(1):2333790./Head Neck. 2024 Sep 18./Heliyon. 2024 Feb 20./Hepatol Commun. 2023 Aug 31;7(9):e0232./Hum Cell. 2022 Jun 24./Hum Cell. 2025 Feb 25;38(2):60./Hum Exp Toxicol. 2021 Jul 5;9603271211030554./Immun Ageing. 2023 Nov 21;20(1):66./Immun Inflamm Dis. 2023 Apr 12; 11:e830./Immun Inflamm Dis. 2023 Oct 20./Inflammation. 2024 Oct 29./Int Immunopharmacol. 2022 Jan 10;104:108443./Int Immunopharmacol. 2023 Aug 23;124(Pt A):110810./Int Immunopharmacol. 2024 Nov 12;143(Pt 3):113615./Int Immunopharmacol. 2025 Jan 4:147:113935./Int J Biol Macromol. 2020 Dec 1;164:2761-2768./Int J Biol Macromol. 2022 Jun 16;S0141-8130(22)01308-3./Int J Biol Macromol. 2023 Apr 6;124342./Int J Biol Macromol. 2023 Feb 23;123816./Int J Biol Macromol. 2024 Feb 12:130076./Int J Biol Macromol. 2024 Jul 27:134120./Int J Biol Macromol. 2024 Jun 13;273(Pt 2):133134./Int J Biol Macromol. 2024 Mar 26:131151./Int J Biol Macromol. 2024 Sep 17:135764./Int J Biol Macromol. 2025 Jan 28:301:140445./Int J Biol Macromol. 2025 Jan 30:302:140531./Int J Biol Sci. 2022 Aug 29;18(14):5459-5474./Int J Biol Sci. 2022 May 1;18(8):3122-3136./Int J Biol Sci. 2022; 18(15):5943-5962./Int J Biol Sci. 2023 Aug 15; 19(13):4223-4241./Int J Biol Sci. 2023 Feb 27;19(5):1471-1489./Int J Biol Sci. 2024 Feb 4;20(4):1471-1491./Int J Chron Obstruct Pulmon Dis. 2023 Jun 26;18:1319-1332./Int J Mol Med. 2021 Jul;48(1):124./Int J Mol Sci. 2022 Jul 24;23(15):8148./Int J Mol Sci. 2023 Mar 11./Int J Mol Sci. 2024 Apr 29;25(9):4853./Int J Mol Sci. 2024 Sep 29;25(19):10509./Int J Oral Sci. 2024 May 8;16(1):35./iScience. 2023 Nov 15./iScience. 2024 Aug 20;27(9):110757./iScience. 2024 Jun 04./iScience. 2024 Sep 30;27(11):111071./iScience. 30 June 2022, 104690./J Adv Res. 2023 Sep 28:S2090-1232(23)00291-6./J Adv Res. 2025 Jan 4:S2090-1232(25)00003-7./J Agric Food Chem. 2020 Nov 11;68(45):12617-12630./J Agric Food Chem. 2022 Dec 15./J Agric Food Chem. 2023 May 3./J Agric Food Chem. 2024 Jun 24./J Anim Sci Biotechnol. 2022 Nov 4;13(1):125./J Anim Sci Biotechnol. 2023 May 3;14(1):61./J Anim Sci Biotechnol. 2024 Sep 5;15(1):119./J Asian Nat Prod Res. 2023 Oct 27:1-13./J Cancer. 2023 Aug 6; 14(13): 2491-2516./J Cell Mol Med. 2020 Oct;24(19):11558-11572./J Cell Mol Med. 2020;00:1-15./J Cell Mol Med. 2021 Jul 18./J Cell Mol Med. 2023 Nov 16./J Cell Mol Med. 2025 Jan;29(1):e70350./J Cell Physiol. 2021 May;236(5):3641-3659./J Cell Physiol. 2022 May 17./J Cell Physiol. 2024 Aug 11:e31364./J Clin Invest. 2020 Jun 1;130(6):3253-3269./J Cosmet Dermatol. 2023 Aug 27./J Dairy Sci. 2023 May 22;S0022-0302(23)00275-8./J Ethnopharmacol. 2023 Feb 11;116259./J Ethnopharmacol. 2024 Aug 3:118658./J Exp Clin Cancer Res. 2022 Mar 30;41(1):116./J Exp Clin Cancer Res. 2023 Jun 19;42(1):150./J Exp Clin Cancer Res. 2024 Jun 26;43(1):177./J Extracell Vesicles. 2023 Jul;12(7):e12342./J Extracell Vesicles. 2024 Jul;13(7):e12468./J Funct Foods. 2023 Oct, 109, 105770./J Funct Foods. 2024 Oct./J Funct Foods. November 2021, 104686./J Gastroenterol. 2024 Apr 29./J Gene Med. 2024 Sep;26(9):e3737./J Hazard Mater. 2022, 126770./J Hazard Mater. 2022: 130623./J Hazard Mater. 2023 Jan 12./J Hazard Mater. 2023 Jul 5,453,131354./J Hazard Mater. 2024 Apr 28:472:134466./J Immunother Cancer. 2022;10:e005668./J Immunother Cancer. 2023 Jan;11(1):e005592./J Immunother Cancer. 2024 Nov 24;12(11):e009805./J Inorg Biochem. 2022 Jun 12;234:111901./J Med Chem. 2023 Oct 20./J Med Chem. 2025 Feb 19./J Med Entomol. 2021 May 15;58(3):1202-1209./J Med Virol. 2021 Oct;93(10):5825-5832./J Med Virol. 2024 Oct;96(10):e29945./J Nanobiotechnology. 2022 Mar 15;20(1):131./J Nanobiotechnology. 2023 Mar 21;21(1):99./J Nanobiotechnology. 2023 Oct 3;21(1):360./J Nat Prod. 2022 Aug 17./J Nat Prod. 2023 Apr 12./J Neuroendocrinol. 2024 Oct 1:e13448./J Neuroinflammation. 2021 Jan 5;18(1):5./J Neuroinflammation. 2024 Dec 23;21(1):327./J Neurosci. 2022 Jun 22;42(25):4958-4979./J Nippon Med Sch. 2023;90(1):89-95./J Ocul Pharmacol Ther. 2022 Jun;38(5):331-338./J Periodontol. 2023 Jul 29./J Pharm Anal. 2025 Jan 28./J Physiol Biochem. 2021 Apr 22;1-11./J Pineal Res. 2021 Dec;71(4):e12774./J Transl Med. 2023 Aug 25;21(1):572./J Transl Med. 2023 Dec 17;21(1):916./J Transl Med. 2024 Dec 27;22(1):1151./J Transl Med. 2024 Dec 3;22(1):1095./J Transl Med. 2024 May 14;22(1):457./J Virol. 2021 Dec 1;JVI0110321./J Virol. 2021 Sep 29;JVI0134521./J Virol. 2022 Jul 19;e0080722./J Virol. 2023 Apr 11;e0030223./J Virol. 2023 Aug 11;e0018123./J Virol. 2023 Nov 27:e0133823./J Virol. 2024 Aug 30:e0104824./J Virol. 2024 Feb 20;98(2):e0190923./J Virol. 2025 Feb 20:e0198024./J Zhejiang Univ Sci B. 2020 Jul;21(7):560-570./Mar Drugs. 2023, 21(3), 151./Mar Drugs. 2024 Apr 13, 22(4), 174./Mbio. 2022 Jan 25;13(1):e0233021./Mbio. 2022 Sep 15;e0143422./mBio. 2024 Sep 17./MedComm (2020). 2024 Jun 27;5(7):e611./MedComm. 2024 Apr 4;5(4):e520./Mediators Inflamm. 2024 Oct 18:2024:9550301./Medical University of South Carolina. 2023 Aug 12./Metabolism. 2024 Oct 19:156050./Mol Biomed. 2023 Nov 17;4(1):42./Mol Cancer. 2024 Apr 29;23(1):86./Mol Cell Biochem. 2023 Sep 22./Mol Cell Biochem. 2024 May 24./Mol Cell Biochem. 2024 Nov 6./Mol Cell Biochem. 2025 Mar 14./Mol Cell Endocrinol. 2024 Aug 8:112338./Mol Cell Probes. 2024 Jul 5:76:101968./Mol Cell Proteomics. 2023 Jul 31;100628./Mol Immunol. 2021 Dec 21;141:318-327./Mol Med Rep. 2024 May;29(5):71./Mol Med. 2023 Jan 16;29(1):6./Mol Med. 2024 May 23;30(1):69./Mol Med. 2024 Nov 15;30(1):219./Mol Med. 2024 Oct 18;30(1):180./Mol Med. 2024 Sep 12;30(1):147./Mol Med. 2025 Jan 23;31(1):21./Mol Neurobiol. 2024 Jul 2./Mol Nutr Food Res. 2023 Sep 29:e2300112./Mol Pharm. 2024 May 9./Mol Ther. 2022 May 10;S1525-0016(22)00304-5./Molecules. 2022 Apr 9;27(8):2431./Molecules. 2022 Dec 2;27(23):8475./Molecules. 2024 Jan 15, 29(2), 417./Nano Today. 2024 Feb, 54, 102090./Nano Today. 2025 Apr./Nano Today. October 2022, 101600./Nat Biotechnol. 2022 Dec;40(12):1834-1844./Nat Cell Biol. 2024 Jul 12./Nat Cell Biol. 2025 Mar 3./Nat Commun. 2023 Jan 17;14(1):265./Nat Commun. 2023 Sep 21;14(1):5891./Nat Commun. 2024 Jan 17;15(1):584./Nat Commun. 2024 Jul 26;15(1):6311./Nat Commun. 2024 May 7;15(1):3805./Nat Commun. 2024 Nov 6;15(1):9578./Nat Commun. 2025 Jan 2;16(1):339./Nat Nanotechnol. 2024 Oct 28./Nature. 2022 Dec;612(7941):725-731./Nature. 2023 Jun;618(7966):799-807./Naunyn Schmiedebergs Arch Pharmacol. 2024 Apr 3./Neoplasia. 2021 Nov 8;23(12):1227-1239./Neoplasia. 2024 Jun 29:55:101015./Neuro Oncol. 2023 Apr 21;noad079./Neurochem Res. 2021 Oct 27;1-12./Neuroscience. 2021 Feb 15;S0306-4522(21)00080-4./Neurotherapeutics. 2020 Oct;17(4):1796-1812./Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121./Nutr Metab. 2021 Sep 9;18(1):83./Nutrients. 2024 Nov 13;16(22):3869./Oncogene. 2022 Jun 30./Oncol Lett. 2021 Mar 29./Oncol Lett. 2024 Feb 2;27(4):140./Oncol Rep. 2021 Feb 3./Oncol Rep. 2024 Jul;52(1):94./Oncol Rep. 2025 Feb;53(2):31./Oncotargets Ther. 2021 Jan 8;13:13437-13450./Open Biol. 2024 Apr;14(4):240001./Osteoarthritis Cartilage.2024 May 6:S1063-4584(24)01175-0./Oxid Med Cell Longev. 04 Aug 2022./Part Fibre Toxicol. 2020 Sep 18;17(1):46./Pharm Biol. 2024 Dec;62(1):214-221./Pharmaceuticals. 2022, 15(12), 1509/Pharmaceuticals. 2023, 16(1), 113./Pharmaceutics. 2024 Dec 21;16(12):1620./Pharmacol Res. 2022 Dec 16;106613./Pharmacol Res. 2024 Feb 13:201:107097./Pharmacological Research-Modern Chinese Medicine. 29 August 2022, 100157./Phytomedicine. 16 June 2022, 154280./Phytomedicine. 2022./Phytomedicine. 2024 Apr 23:129:155675./Phytomedicine. 2024 Feb 1, 155401./Phytomedicine. 2024 Jan 9, 155351./Phytomedicine. 2024 Sep 21./Phytomedicine. 2025 Apr./Phytomedicine. 2025 Feb 25:140:156577./Phytomedicine. 2025 Jan 22:138:156404./Phytomedicine. December 2022, 154477./Phytother Res. 2022 Oct 17./Phytother Res. 2022 Sep 9./Phytother Res. 2023 Feb 8./Phytother Res. 2024 Mar 25./PLoS Negl Trop Dis. 2023 May 4;17(5):e0011281./PLoS Pathog. 2021 Jun 2;17(6):e1009645./PLoS Pathog. 2024 Apr 12;20(4):e1012123./PLoS Pathog. 2024 Aug 13;20(8):e1012461./PLoS Pathog. 2024 Mar 18;20(3):e1012110./PLoS Pathog. 2024 Sep 10;20(9):e1012535./PLoS Pathog. 2025 Jan 2;21(1):e1012800./Poult Sci. 2024 Nov 27;104(1):104601./Poultry Sci. 2023 Jan 25./Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2403685121./Protein Cell. 21 September 2022./Redox Biol. 2021 Jan;38:101828./Redox Biol. 2023 Dec 20:69:103008./Redox Biol. 2023 Jul, 63, 102751./Redox Biol. 2024 Dec 5:79:103460./Redox Biol. 2024 Sep:75:103277./Reprod Biol. 2023 Dec 30;24(1):100846./Res Sq. 2024 Jun 25./Res Sq. 2024 Nov 18./Res Sq. 2024 Nov 26./Res Sq. 2024 Oct 27./Research Square Preprint. 2020 Oct./Research Square Preprint. 2021 Feb./Research Square Preprint. 2021 Mar./Research Square Preprint. 2022 Feb./Research Square Preprint. 2023 Apr 6./Research Square Preprint. 2023 Dec 29./Research Square Preprint. 2023 Jun 12./Research Square Preprint. 2023 May 24./Research Square Preprint. 2023 May 26./Research Square Preprint. 2023 Nov 14./Research Square Preprint. 2023 Oct 13./Research Square Preprint. 2023 Sep 11./Research Square Preprint. 2023 Sep 7./Research Square Preprint. 2024 Apr 22./Research Square Preprint. 2024 Apr 29./Research Square Preprint. 2024 Dec 03./Research Square Preprint. 2024 Mar 19./Research Square Preprint. 2024 Nov 26./Research Square Preprint. 2025 Jan 08./Research Square Print. 2022 Sep./Research Square Print. 2023 Mar 24./Research Square Print. August 18th, 2022./Research Square Print. October 14th, 2022./Research Square Print. September 20th, 2022./Respir Res. 2024 Dec 4;25(1):425./Respir Res. 2024 May 20;25(1):215./Sci Adv. 2023 Oct 13;9(41):eadh1134./Sci Rep. 2023 Jul 3;13(1):10752./Sci Rep. 2024 Mar 18;14(1):6504./Sci Rep. 2024 May 3;14(1):10160./Sci Rep. 2024 Oct 8;14(1):23494./Sci Rep. 2024 Sep 30;14(1):22624./Sci Signal. 2022 Dec 20;15(765):eabo4356./Sci Total Environ. 2021, 146523./Sci Total Environ. 2022 Jan 2;814:152759./Sci Total Environ. 2023 May 16;164172./Small. 2021 Aug;17(32):e2101368./Spine J. 2024 Nov 8:S1529-9430(24)01096-9./SSRN. 15 Oct 2022./SSRN. 2023 Aug 4./SSRN. 2023 Feb 14./SSRN. 2023 Nov 28./SSRN. 2023 Oct 12./SSRN. 2024 Apr 19./SSRN. 2024 Jun 18./SSRN. 2024 May 2./SSRN. 2025 Feb 18./Stem Cells Int. 0 Sept 2022./Theranostics. 2020 Jul 1;10(18):8051-8060. /Theranostics. 2021 Jan 1;11(2):841-860./Theranostics. 2021 Mar 4;11(10):4637-4654./Theranostics. 2024 Jul 1;14(10):3984-3996./Theriogenology. 2023 Jan 15, 214, 342-351./Toxicol Appl Pharmacol. 2020 Dec 15;409:115271./Toxicol Appl Pharmacol. 2020 Nov 15;407:115241./Toxicol Appl Pharmacol. 2022 Aug 30;116214./Toxicol Appl Pharmacol. 2022 Jun 1;444:116037./Toxicol Appl Pharmacol. 31 December 2021, 115857./Toxicol In Vitro. 2023 Oct 11:105711./Toxicol Lett. 18 July 2022./Toxicology. 2023 Apr 14;153512./Toxicon. 2025 Jan 7:108233./Traffic. 2022 Nov 22./Transl Oncol. 2024 Mar 14:44:101938./Transl Oncol. 2024 May 3:45:101981./Transl Oncol. 2024 Nov 27:51:102214./Trop Med Infect Dis. 2024 Feb 4;9(2):42./Vet Microbiol. 2021, 109103./Vet Microbiol. 2021, 109177./Vet Microbiol. 2023 Apr 29;282:109767./Vet Microbiol. 2023 Aug 15;284:109851./Vet Microbiol. 2023 Jan 24;279:109666./Vet Microbiol. 2024 Jul 22:297:110190./Vet Microbiol. 2024 Jun 20:295:110160./Vet Res. 2024 Apr 8;55(1):45./Vet Res. 2024 Nov 14;55(1):151./Virol Sin. 2023 May 6;S1995-820X(23)00051-2./Virol Sin. 2024 Jan 23:S1995-820X(24)00005-1./Virol Sin. 2024 Jun 28:S1995-820X(24)00108-1./Virus Res. 2022 Jul 2;315:198794./Viruses. 2020 Jun 10;12(6):628./Acta Biochim Biophys Sin (Shanghai). 2016 Dec;48(12):1075-1084./Acta Biochim Biophys Sin (Shanghai). 2018 Feb 1;50(2):144-155./Acta Biomater. 2023 May 5;S1742-7061(23)00248-9./Acta Pharm Sin B. 2021 May;11(5):1246-1260./Acta Pharmacol Sin. 2024 Dec 11./Acta Physiol (Oxf). 2019 Aug;226(4):e13272. /Adv Sci (Weinh). 2024 Jan 6:e2305260./Adv Sci (Weinh). 2019 Mar 25;6(10):1801862./Aging (Albany NY). 2019 Nov 15; 11(21): 9794–9810./Aging Cell. 2020 Jul;19(7):e13171. /Aging. 2021 Mar 10;13(7):9542-9565./Am J Cancer Res. 2019 Jun 1;9(6):1266-1281./Am J Chin Med. 2019;47(6):1405-1418./Anticancer Agents Med Chem. 2017;17(8):1093-1101. /Atherosclerosis. 2019 Feb 22;284:1-10./Autophagy. 2020 Jan;16(1):106-122. /Autophagy. 2021 Jul;17(7):1592-1613./Autophagy. 2023 Jan 12;1-11./Autophagy. 2023 Jun 13;1-17./Autophagy. 2025 Mar 17./Biochem Biophys Res Commun. 2018 Sep 5;503(2):501-507./Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868./Biochim Biophys Acta Mol Basis Dis. 2019 Jun 26;1865(10):2618-2632. /Biomed J. 2020 Aug;43(4):368-374./Biomed Pharmacother. 2018 Dec;109:1617-1627./Biomed Pharmacother. 2019 Oct;118:109144./Biomed Pharmacother. 2020 Jun;126:110080./Biomed Pharmacother. 2020 Mar;123:109811./Biomed Pharmacother. 2023 Mar 24;162:114555./bioRxiv. 2020 Jun./bioRxiv. 2024 September 10./BMC Pharmacol Toxicol. 2022 Jun 18;23(1):41./Br J Pharmacol. 2020 Aug;177(15):3473-3488. /Br J Pharmacol. 2025 Jan 28./Breast Cancer Res. 2021 Dec 18;23(1):116./Can J Physiol Pharmacol. 2020 Jul;98(7):449-458./Cancer Invest. 2019;37(6):242-252. /Cancer Lett. 2020 Jul 1;481:15-23./Cell Death Differ. 2022 Sep 14./Cell Death Dis. 2019 Jul 22;10(8):565./Cell Death Dis. 2020 Jul 30;11(7):607./Cell Death Dis. 2020 Nov 11;11(11):969./Cell Death Dis. 2021 Apr 20;12(5):413./Cell Death Dis. 2022 Aug 16;13(8):711./Cell Death Dis. 2024 Nov 11;15(11):814./Cell Death Dis. 2019 Feb 11;10(2):118./Cell Death Dis. 2019 Jun 11;10(6):456. /Cell Death Discov. 2021 Dec 14;7(1):392./Cell Physiol Biochem. 2018;48(6):2318-2336. /Cell Prolif. 2019 May;52(3):e12606. /Cell Prolif. 2019 May;52(3):e12609./Cell Rep. 2022 Oct 4;41(1):111435./Cell Rep. 2023 Aug 29;42(8):112851./Cell Signal. 2024 Dec 3:111534./Cell Signal. 2024 Mar 11:118:111136./Chem Biol Interact. 2018 Mar 1;283:59-74./Chem Biol Interact. 2024 Apr 10:395:110999./Chem Eng J. 15 May 2022, 135256./Chem Res Toxicol. 2019 Dec 16;32(12):2509-2516./Circ Res. 2018 May 25;122(11):1532-1544./Clin Cosmet Investig Dermatol. 2024 May 14:17:1093-1105./Clin Transl Med. 2020 Oct;10(6):e208./Commun Biol. 2024 Jul 17;7(1):872./Comput Struct Biotechnol J. 2022 Aug 30./DNA Cell Biol. 2020 Mar;39(3):368-378. /EBioMedicine. 2017 May;19:49-59./Elife. 2021 Jul 13;10:e69047./Environ Pollut. 2020, 116413./Exp Cell Res. 2018 Dec 15;373(1-2):211-220./Exp Cell Res. 2018 Feb 15;363(2):160-170./FASEB J. 2020 Aug;34(8):10966-10983./Food Funct. 2019 Oct 16;10(10):6915-6926./Free Radic Biol Med. 2023 Sep 17;S0891-5849(23)00641-X./Front Cell Infect Microbiol. 2020 Apr 15;10:155./Front Microbiol. 2020 Jan 8;10:3040./Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. 2020 Sep./Gene Dis. 2019 May 25;7(3):401-407./Genes Dis. 2021 Mar 1./Heliyon. 2024 Jan 16./Hum Cell. 2024 Oct 22;38(1):4./In Vitro Cell Dev Biol Anim. 2019 Oct;55(9):703-712. /Inflammation. 2020 Aug;43(4):1510-1523./Int Immunopharmacol. 2020 Nov;88:106859./Int J Biol Macromol. 2023 Nov 28, 128451./Int J Biol Macromol. 2025 Jan 27:140362./Int J Biol Sci. 2019 Jan 29;15(4):788-799. /Int J Biol Sci. 2019 May 12;15(6):1310-1324./Int J Biol Sci. 2022; 18(9):3747-3761./Int J Biol Sci. 2019 Mar 10;15(5):942-952/Int J Mol Med. 2018 May;41(5):2535-2544./Int J Mol Med. 2020 Jan;45(1):245-254./Int J Mol Sci. 2017 May 19;18(5). pii: E1063./Int J Mol Sci. 2019 Feb 28;20(5):1057./Invest New Drugs. 2021 Jan 2./iScience. 2024 Feb 8;27(3):109181./J Biol Chem. 2021, 100616./J Cell Biochem. 2020 Jun;121(5-6):3333-3344./J Cell Mol Med. 2018 Nov;22(11):5311-5321./J Cell Mol Med. 2021 Oct;25(19):9214-9227./J Diabetes. 2019 Oct;11(10):826-836. /J Exp Clin Cancer Res. 2019 Aug 14;38(1):354. /J Immunol. 2023 Jan 30;ji2200544./J Infection. 2020 Jun;80(6):e19-e26./J Med Virol. 2022 Oct 10./J Microbiol. 2020 Apr;58(4):320-329./J Nutr Biochem. 2020 Jun;80:108380./J Pharmacol Exp Ther. 2018 Oct;367(1):20-27./J Transl Med. 2025 Jan 16;23(1):74./J Virol. 2022 Sep 14;96(17):e0094422./Microbiol Spectr. 2023 Feb 23;e0438622./Mol Cancer. 2019 Apr 10;18(1):85./Mol Cell Biochem. 2020 Sep;472(1-2):219-230./Mol Med. 2023 Jul 24;29(1):99./Mol Oncol. 2020 Nov 23;15(2):725-738./Molecules. 2019 Mar 20;24(6):1091./Nat Struct Mol Biol. 2024 May 20./Neural Regen Res. 2021 Apr;16(4):765-771./Neurosci Lett. 2018 Aug 24;682:112-117. /Neurosci Lett. 2019 Nov 1;712:134485./Neurotox Res. 2020 Dec;38(4):859-870./Nucleic Acids Res. 2018 Apr 20;46(7):3284-3297./Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121./Nutr Metab. 2021 Feb 18;18(1):20./Oncogene. 2018 May;37(22):2936-2952./Oncotarget. 2017 Nov 22;8(65):109135-109150. /Oxid Med Cell Longev. 2020 Aug 20;2020:4964202./Oxid Med Cell Longev. 2020 Oct 23;2020:2048210./Phytomedicine. 2025 Jan 13:138:156389./Phytother Res. 2023 Mar 6./PLoS Negl Trop Dis. 2019 Aug 20;13(8):e0007681. /Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23332-23338. /Prostate. 2019 Jan;79(1):44-53. /Research Square Preprint. 2021 May./Research Square Preprint. 2021 Oct./Research Square Preprint. 2024 Mar 20./Research Square Print. 2022 May./Respir Res. 2018 Dec 5;19(1):243. /Sci Rep. 2017 Jun 7;7(1):2929./Sci Rep. 2018 Mar 7;8(1):4108./Sci Rep. 2020 May 7;10(1):7714./Sci Rep. 2020 Mar 5;10(1):4126. /Theriogenology. 1 January 2022, Pages 1-10./Theriogenology. 2019 Dec;140:44-51./Toxicol In Vitro. 2024 Sep 13:105941./Toxicol Lett. 2020 Mar 15;321:32-43./Tumour Biol. 2016 Jul;37(7):8811-24. /Vaccines. 2020 Jan 13;8(1):22./Vet Res. 2023 Mar 14;54(1):23./Virol J. 2019 Jul 18;16(1):90.

References: [1]Said A, et al. Chloroquine promotes IL-17 production by CD4+ T cells via p38-dependent IL-23 release by monocyte-derived Langerhans-like cells. J Immunol. 2014 Dec 15;193(12):6135-43./[2]Tuomela J, et al. Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer. Oncol Lett. 2013 Dec;6(6):1665-1672./[3]Mohamed FE, et al. Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma. Liver Int. 2014 Jul 2. doi: 10.1111/liv.12626./[4]Colson P, et al. Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents. 2020;55(4):105932./[5]Savarino A, et al. The anti-HIV-1 activity of chloroquine. J Clin Virol. 2001;20(3):131-135.

CAS Number: 3545-67-3

Molecular Weight: 392.79

Compound Purity: 99.10

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: H2O : 100 mg/mL (ultrasonic)

Target: Antibiotic;Autophagy;HIV;Parasite;SARS-CoV;Toll-like Receptor (TLR)
More Information
SKU MEXHY-17589B-10
Manufacturer MedChemExpress
Manufacturer SKU HY-17589B-10
Package Unit 10 mg
Quantity Unit STK
Product information (PDF)
×
MSDS (PDF)
×