CHPG (sodium salt) (Standard), CAS 1303993-73-8

CHPG (sodium salt) (Standard), CAS 1303993-73-8
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MEXHY-101364AR-0
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MedChemExpress

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Product Description: CHPG (sodium salt) (Standard) is the analytical standard of CHPG (sodium salt). This product is intended for research and analytical applications. CHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells[1]. CHPG sodium salt protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways.[2].

Formula: C8H7ClNNaO3

References: [1]Qiu JL, et al. The selective mGluR5 agonist CHPG attenuates SO<sub>2</sub>-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. Neurochem Int. 2015 Jun-Jul;85-86:46-52./[2]Chen T, et al. The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway. Int J Mol Med. 2012 Apr;29(4):630-6.

CAS Number: 1303993-73-8

Molecular Weight: 223.59

Research Area: Inflammation/Immunology; Neurological Disease

Target: Akt;ERK;mGluR;NF-κB;Reference Standards
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SKU MEXHY-101364AR-0
Manufacturer MedChemExpress
Manufacturer SKU HY-101364AR-0
Package Unit Get quote
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