CK1δ-IN-9, CAS 3057263-82-5

Product Description: CK1δ-IN-9 (Compound 8) is the inhibitor for casein kinase 1 that inhibits CK1δ with IC50 of 1.4 nM. CK1δ-IN-9 inhibits p38α and p38β with IC50 of 0.25 μM and 0.78 μM. CK1δ-IN-9 exhibits pharmacokinetic characteristics with a good oral bioavailability (70%) and a moderate clearance[1].

Formula: C16H12FN5

References: [1]McCarver S, et al., Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions. ACS Med Chem Lett. 2024 Mar 7;15(4):486-492.

CAS Number: 3057263-82-5

Molecular Weight: 293.30

Research Area: Others

Target: Casein Kinase;p38 MAPK

• SKU: MEXHY-171292-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171292-0
• Package Unit: Get quote
• Quantity Unit: STK