CLK2/3-IN-1

Product Description: CLK2/3-IN-1 (Compound 7c) is an orally active CLK2/3 inhibitor (EC50: 5.07 nM and 30.03 nM, respectively). CLK2/3-IN-1 binds to Lys193 and Lys186 of CLK2/3 via hydrogen bonds. CLK2/3-IN-1 can inhibit the proliferation of SW480 tumor cells (IC50: 163 nM). CLK2/3-IN-1 can be used to study CLK-related tumor diseases[1].

Formula: C24H25N7O

References: [1]Wei J, et al. Discovery of novel pyridine skeleton derivatives as potent CLK2/3 inhibitors. Bioorg Med Chem Lett. 2025 Aug 1;123:130212.

Molecular Weight: 427.50

Research Area: Cancer

Target: CDK

• SKU: MEXHY-173510-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173510-0
• Package Unit: Get quote
• Quantity Unit: STK