Clofarabine-5'-triphosphate (trisodium)

Product Description: Clofarabine-5'-triphosphate trisodium is the trisodium salt form of Clofarabine-5'-triphosphate (HY-164840). Clofarabine-5'-triphosphate trisodium is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-triphosphate trisodium exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair[1].

Formula: C10H11ClFN5Na3O12P3

References: [1]Nagai S, et al., Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity. Cancer Res. 2011 Mar 1;71(5):1781-91.

Molecular Weight: 609.56

Compound Purity: 99.54

Research Area: Cancer

Target: DNA/RNA Synthesis

• SKU: MEXHY-164840A-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-164840A-10
• Package Unit: 10 mg
• Quantity Unit: STK