Product Description: Crinecerfont tosylate (SSR-125543 tosylate) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont tosylate can be used for Classic congenital adrenal hyperplasia (CAH) research[1]. Crinecerfont tosylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Applications: Metabolism-protein/nucleotide metabolism
Formula: C34H36ClFN2O4S2
References: [1]Newfield R S, et al. Crinecerfont, a CRF1 receptor antagonist, lowers adrenal androgens in adolescents with congenital adrenal hyperplasia[J]. The Journal of Clinical Endocrinology & Metabolism, 2023, 108(11): 2871-2878.
CAS Number: 2649012-17-7
Molecular Weight: 655.24
Research Area: Metabolic Disease
Target: CFTR
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