CRK12-IN-1, CAS 1990479-14-5

Product Description: CRK12-IN-1 is a potent CRK12 inhibitor. CRK12-IN-1 is extremely potent against T.b. brucei and rapidly cytocidal, as well as equally potent against T. congolense and T. vivax (EC50 of 1.3 and 18 nM, respectively)[1].

Applications: COVID-19-immunoregulation

Formula: C20H26F2N4O3S2

References: [1]Smith A, et al. Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis [published online ahead of print, 2022 Mar 18]. J Med Chem. 2022;10.1021/acs.jmedchem.1c02104.

CAS Number: 1990479-14-5

Molecular Weight: 472.57

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Parasite

• SKU: MEXHY-145812-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145812-1
• Package Unit: 1 mg
• Quantity Unit: STK