CTT2274

Product Description: CTT2274 is a prodrug of MMAE (HY-15162). CTT2274 is composed of a prostate-specific membrane antigen (PSMA)-binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and MMAE payload. CTT2274 shows selective binding to PSMA and delivers MMAE. CTT2274 inhibits prostate cancer[1].

Formula: C119H159N17O33P2

References: [1]Bomba HN, et al. A Unique Prodrug Targeting the Prostate-Specific Membrane Antigen for the Delivery of Monomethyl Auristatin E. Bioconjug Chem. 2025 Feb 19;36(2):169-178.Bomba HN, et al. A Unique Prodrug Targeting the Prostate-Specific Membrane Antigen for the Delivery of Monomethyl Auristatin E. Bioconjug Chem. 2025 Feb 19;36(2):169-178.

Molecular Weight: 2417.58

Research Area: Cancer

Target: PSMA

• SKU: MEXHY-168913-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168913-0
• Package Unit: Get quote
• Quantity Unit: STK